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1 · Prediction of maternal and foetal exposures to perfluoroalkyl
2 · PBPK modeling to support risk assessment of pyrethroid
3 · Metabolomics
4 · Estimating the cumulative human exposures to pyrethroids by
5 · Estimating human exposure to pyrethroids' mixtures from
6 · Céline Brochot
7 · Céline BROCHOT (0000
8 · Céline BROCHOT
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[email protected] – HBM4EU – science and policy for
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Céline BROCHOT, Senior Principal Scientist | Cited by 2,419 | of Certara, NJ | Read 127 publications | Contact Céline BROCHOTCertara France: Paris, Île-de-France, FR. 2023-01-02 to present | Senior principal scientist (Simcyp) Employment. Show more detail. Source : Céline BROCHOT.Electronic address: [email protected]. PMID: 33031810. DOI: 10.1016/j.envres.2020.110281. Abstract. Human biomonitoring data provide evidence to .
Human biomarkers of exposure to pyrethroid insecticides are usually urinary concentrations of metabolites that can be specific to a pyrethroid or common to several . 188 relations sur LinkedIn. Consultez le profil de Céline Brochot sur LinkedIn, une communauté professionnelle d’un milliard de membres. Prenatal exposures to perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) have been associated with child health outcomes, but many of these associations .Dr Céline Brochot, PhD. in biomathematics (University of Paris VI, France). She is involved in several EU projects (Predict-IV on prediction of chronic toxicity, COSMOS on developing in .
The HBM4EU project was launched in 2016 with the aim of improving the collective understanding of human exposure to hazardous chemicals and developing HBM as an exposure assessment .
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In this work, we combined the recently developed “metabolomics-on-a-chip” approach with metabolic flux analysis to model the metabolic network of the hepatoma HepG2/C3A cell line .Thépaut, Elisa ; Bisson, Michèle ; Brochot, Céline et al. / PBPK modeling to support risk assessment of pyrethroid exposure in French pregnant women. In: Environmental Research. .Céline BROCHOT, Senior Principal Scientist | Cited by 2,419 | of Certara, NJ | Read 127 publications | Contact Céline BROCHOTElectronic address: [email protected]. PMID: 33031810. DOI: 10.1016/j.envres.2020.110281. Abstract. Human biomonitoring data provide evidence to exposure of environmental chemicals.
Certara France: Paris, Île-de-France, FR. 2023-01-02 to present | Senior principal scientist (Simcyp) Employment. Show more detail. Source : Céline BROCHOT.
Prediction of maternal and foetal exposures to perfluoroalkyl
Dr Céline Brochot, PhD. in biomathematics (University of Paris VI, France). She is involved in several EU projects (Predict-IV on prediction of chronic toxicity, COSMOS on developing in silico. Human biomarkers of exposure to pyrethroid insecticides are usually urinary concentrations of metabolites that can be specific to a pyrethroid or common to several compounds. We developed a global toxicokinetic model that links the external exposure to four widely-used pyrethroids and their isomers ..
188 relations sur LinkedIn. Consultez le profil de Céline Brochot sur LinkedIn, une communauté professionnelle d’un milliard de membres.
Prenatal exposures to perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) have been associated with child health outcomes, but many of these associations remain poorly characterized.The HBM4EU project was launched in 2016 with the aim of improving the collective understanding of human exposure to hazardous chemicals and developing HBM as an exposure assessment method. The project had €74m in funding and jointly implemented by 120 partners from 28 participating countries – 24 EU member states plus Norway, Switzerland .
In this work, we combined the recently developed “metabolomics-on-a-chip” approach with metabolic flux analysis to model the metabolic network of the hepatoma HepG2/C3A cell line and to infer the distribution of intracellular metabolic fluxes . Brochot, Céline and Bois, Frédéric Y., Use of a Chemical Probe to Increase Safety for Human Volunteers in Toxicokinetic Studies. Risk Analysis, Vol. 25, No. 6, pp. 1559-1571, December 2005, Available at SSRN: https://ssrn.com/abstract=943167 or http://dx.doi.org/10.1111/j.1539-6924.2005.00682.xCéline BROCHOT, Senior Principal Scientist | Cited by 2,419 | of Certara, NJ | Read 127 publications | Contact Céline BROCHOT
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Electronic address: [email protected]. PMID: 33031810. DOI: 10.1016/j.envres.2020.110281. Abstract. Human biomonitoring data provide evidence to exposure of environmental chemicals.Certara France: Paris, Île-de-France, FR. 2023-01-02 to present | Senior principal scientist (Simcyp) Employment. Show more detail. Source : Céline BROCHOT.
Dr Céline Brochot, PhD. in biomathematics (University of Paris VI, France). She is involved in several EU projects (Predict-IV on prediction of chronic toxicity, COSMOS on developing in silico. Human biomarkers of exposure to pyrethroid insecticides are usually urinary concentrations of metabolites that can be specific to a pyrethroid or common to several compounds. We developed a global toxicokinetic model that links the external exposure to four widely-used pyrethroids and their isomers .. 188 relations sur LinkedIn. Consultez le profil de Céline Brochot sur LinkedIn, une communauté professionnelle d’un milliard de membres.
Prenatal exposures to perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) have been associated with child health outcomes, but many of these associations remain poorly characterized.The HBM4EU project was launched in 2016 with the aim of improving the collective understanding of human exposure to hazardous chemicals and developing HBM as an exposure assessment method. The project had €74m in funding and jointly implemented by 120 partners from 28 participating countries – 24 EU member states plus Norway, Switzerland .In this work, we combined the recently developed “metabolomics-on-a-chip” approach with metabolic flux analysis to model the metabolic network of the hepatoma HepG2/C3A cell line and to infer the distribution of intracellular metabolic fluxes .
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PBPK modeling to support risk assessment of pyrethroid
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